Chapter 6: DNA: Structure, Replication and Organization Beta
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SBI4U Biology · 6.2
Avery, MacLeod and McCarty
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Avery, MacLeod and McCarty
- In 1944 they used enzymes on extracts of heat-killed S-strain Streptococcus to show that DNA is the transforming substance.
- Each extract was treated with an enzyme that destroys DNA, RNA or protein.
- Each treated extract was mixed with R-strain bacteria and the cultures were observed.
- Cultures still transformed when protein or RNA had been destroyed, but not when DNA had been destroyed, which pointed to DNA.
- Many scientists still favoured protein, so the team hesitated to say DNA was proven.